CONGRATULATIONS TO DR. RABINDRA N. ROY: Prof Rabindra N. Roy was awarded D. Sc degree (earned) from Jadavpur University, India, in December, 1999 on 'Statistical Thermodynamics of Electrolyte Solution'.

CONGRATULATIONS TO DR. SCOTT PETRICH: Dr. Petrich received the 1998 faculty award for teaching from Dr. John E. Moore, Jr., the president of Drury College, and Dr. Stephen H. Good, the vice president of academic affairs and the dean of the Drury University, at Clara Thompson Hall, on August 26,1998.

Proposal for the new Science Building of Drury University.

DR. JOHANN DEISENHOFER, Nobel Laureate, professor of biochemistry, University of Texas Southwestern Medical Center at Dallas, gave a talk on "Half a Century of Structural Biology" in Clara Thompson Hall at 11 a.m. on April 22, 1999.

This is sponsored by the Convocation Committee of Drury College and cosponsored by the Walter Hoffman Department of Chemistry.

Dr. Daniel Kahne, Professor of Chemistry at Princeton University, gave a convocation talk on November 4, 1999. The topic of the talk was on studies of the Glycopeptide Antibiotics. The abstract of the talk is given below.

Vancomycin and related glycopeptide antibiotics inhibit cell wall biosynthesis by binding to the terminal D-Ala-D-Ala dipetide of the peptidoglycan precursor. Resistance arises as microorganisms acquire the ability to substitute D-Ala-D-Lac for the D-Ala-D-Ala, which results in the loss of a key hydrogen bond between the peptide backbone of vancomycin and the substrate. There is evidence that altering the carbohydrates attached to vancomycin can result in dramatic improvements in biological activity. Various hypotheses have been proposed to explain how the carbohydrates are involved. In order to learn more about the role of the carbohydrates in these compounds, chemistry to make carbohydrate derivatives for biological and mechanistic investigation is essential. I will talk about efficient synthetic strategies for exploring changes to the carbohydrates. I will talk about a new mechanism of action which does not require dipetide binding that may explain why various carbohydrate derivatives of vancomycin can kill resistant microorganisms effectively.

Dr. JORGE L. PADRON, Emeritus Professor, Former Chairman of the Chemistry Dept., Former Dean of the College, and Former Acting President of Drury College. Three times Fulbright Scholars, a gifted teacher and an outstanding research worker in the field of biochemistry.

Please send notice submissions to Dr. Roy -

Dr. Rabindra N. Roy, Chair
(417) 873-7247
Hoffman Department of Chemistry
900 North Benton Avenue
Springfield, Missouri 65802